13:50 PM

Departments Team Up to Host Cancer-Related Lecture

RobertChapkin_bigThe Departments of Computer and Mathematical Sciences and Natural Sciences present a joint colloquium by Robert S. Chapkin, Regents Professor and University Faculty Fellow of the Departments of Biochemistry and Biophysics, Veterinary Medicine and Biomedical Sciences, and Microbial and Molecular Pathogenesis at the Texas A&M Health Science Center.

Chapkin will speak on "Teaming up with the Physical Sciences to make sense of chemoprevention data" at 1 p.m. Friday, April 5, in N1099.

In addition to his faculty positions, Chapkin is also a member of the Division of Hematology/Oncology at the Texas A&M Health Science Center Scott & White Hospital/Clinic.

The lecture abstract reads, "Chapkin's lab investigates the impact of dietary fat and fiber on the cellular "signaling cascades" in the colon. His laboratory is involved in systems biology, the modeling and understanding at the molecular level of the dynamic relationships among diet and biological molecules which regulate colon cancer development. He has demonstrated that omega-3 fatty acids regulate the transmission of information that alters physiological responses such as cell growth, differentiation, apoptosis, DNA methylation status, membrane microdomain organization, and protein trafficking, thereby ultimately determining the risk for developing colon cancer. Findings from his studies indicate that the chemopreventive effect of fish oil is due to the direct action of omega-3 fatty acids and not to a reduction in the content of omega 6 fatty acids. He has developed noninvasive methodology for monitoring global changes in intestinal gene expression. This effort has generated a patent and an NIH initiated and sponsored clinical intervention trial."